mhealth Evidence

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mHealth Evidence was launched in 2012 to bring together the world’s literature on “mHealth” (broadly speaking, the application of mobile technologies to health service delivery). The collection was intended to help program managers, researchers, government leaders, donors, software developers, and other key decision-makers quickly get up to speed on the current state-of-the-art and evidence-based best practices. It included 11,000 bibliographic records of peer-reviewed and gray literature from low-, middle- and high-resource settings, with basic and advanced search. The database categorized evidence according to a taxonomy developed in partnership with the World Health Organization’s mHealth Technical and Evidence Review Group (mTERG).

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    Implementing behaviour change theory and techniques to increase physical activity and prevent functional decline among adults aged 61-70: The PreventIT project.
    (0000-00-00) Boulton, Elisabeth; Hawley-Hague, Helen; French, David P; Mellone, Sabato; Zacchi, Anna; Clemson, Lindy; Vereijken, Beatrix; Todd, Chris
    The health and wellbeing benefits of engaging in physical activity PA and of improving strength and balance are well documented The World Health Organization s recommendations of 150 min per week of moderate intensity physical activity have been adopted across the world in policy and practice recommendations However the number of older adults engaging in this level of PA remains low The European Project PreventIT has adapted the Lifestyle integrated Functional Exercise LiFE programme which reduced falls in people 75 years and over for a younger cohort aLiFE aLiFE incorporates challenging strength and balance agility tasks as well as specific recommendations for increasing physical activity and reducing sedentary behaviour in young older adults aged 60 70 years Personalised advice is given on how to integrate strength balance and physical activities into daily life aLiFE has been further developed to be delivered using smartphones and smartwatches eLiFE providing the opportunity to send timely motivational messages and real time feedback to the user Both aLiFE and eLiFE are behaviour change interventions supporting older adults to form long term physical activity habits PreventIT has taken the original LiFE concept and further developed the behaviour change elements explicitly mapping them to Social Cognitive Theory Habit Formation Theory and 30 Behaviour Change Techniques BCTs Goal setting planning prompts and real time feedback are used to deliver a person centred experience Over 1300 motivational messages have been written mapped to psychological theory BCTs and evidence regarding the importance of strength balance and PA A motivational assessment tool has been developed to enable us to investigate stated motivational drivers with actual performed behaviour within the feasibility Randomised Controlled Trial The PreventIT mHealth intervention focusses on behaviour change from initiation to long term maintenance addressing the different phases of adopting a healthier lifestyle As such it makes a strong contribution to the developing field of evidence based mobile health mHealth ABBREVIATIONS AND ACRONYMS
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    Hepatopathies in children and adolescents with type 1 diabetes.
    (0000-00-00) Aydın, Firdevs; Gerenli, Nelgin; Dursun, Fatma; Atasoy, Tülay Öztürk; Kalın, Sevinç; Kırmızıbekmez, Heves
    Background Diabetes and hepatosteatosis are dramatically increasing in childhood Non alcoholic fatty liver disease NAFLD is defined as a common disorder in adulthood especially with type 2 diabetes and metabolic syndrome while very few studies are available on liver health in children with type 1 diabetes Patients and methods One hundred and ten 52 males and 58 females patients with type 1 diabetes aged between 8 and 18 years were examined The lipid profile liver enzymes and hepatobiliary ultrasound findings of patients were investigated in terms of hepatopathies Patients diagnosed with fatty liver were evaluated by pediatric gastroenterology specialists for the differential diagnosis and exclusion of other etiologies The relationships between hepatopathy and age pubertal status the duration of diabetes and glycemic control were evaluated Results Hepatopathy was found in 17 15 5 patients The levels of alanine aminotransferase ALT and aspartate aminotransferase AST were normal and did not correlate with the ultrasonography USG findings Hyperechogenicity detected by USG whether it is true fat or glycogen hepatopathy was found to be associated with poor glycemic control independently of age puberty status and the duration of diabetes Conclusions This study contributes to the literature in terms of the relationship between liver health and glycemic control in pediatric type 1 diabetes Hepatopathies were releated with poor glycemic control independently of the duration of diabetes This suggested that liver disorders should be considered as one of the subacute complications of diabetes It was concluded that routine screening for comorbidities and complications in type 1 diabetes should also include hepatobiliary USG as liver enzymes alone are inadequate for detecting hepatopathies
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    A multi-enzyme cascade reaction for the production of 6-hydroxyhexanoic acid.
    (0000-00-00) Srinivasamurthy, Vishnu S T; Böttcher, Dominique; Bornscheuer, Uwe T
    Multi enzyme cascade reactions capture the essence of nature s efficiency by increasing the productivity of a process Here we describe one such three enzyme cascade for the synthesis of 6 hydroxyhexanoic acid Whole cells of Escherichia coli co expressing an alcohol dehydrogenase and a Baeyer Villiger monooxygenase CHMO for internal cofactor regeneration were used without the supply of external NADPH or NADP The product inhibition caused by the caprolactone formed by the CHMO was overcome by the use of lipase CAL B for in situ conversion into 6 hydroxyhexanoic acid A stirred tank reactor under fed batch mode was chosen for efficient catalysis By using this setup a product titre of 20 g L 1 was achieved in a 500 mL scale with an isolated yield of 81 6 hydroxyhexanoic acid
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    Comparison of Standard Clinical and Instrumented Physical Performance Tests in Discriminating Functional Status of High-Functioning People Aged 61⁻70 Years Old.
    (0000-00-00) Coni, Alice; Ancum, Jeanine M Van; Bergquist, Ronny; Mikolaizak, A Stefanie; Mellone, Sabato; Chiari, Lorenzo; Maier, Andrea B; Pijnappels, Mirjam
    Assessment of physical performance by standard clinical tests such as the 30 sec Chair Stand 30CST and the Timed Up and Go TUG may allow early detection of functional decline even in high functioning populations and facilitate preventive interventions Inertial sensors are emerging to obtain instrumented measures that can provide subtle details regarding the quality of the movement while performing such tests We compared standard clinical with instrumented measures of physical performance in their ability to distinguish between high and very high functional status stratified by the Late Life Function and Disability Instrument LLFDI We assessed 160 participants from the PreventIT study 66 3 2 4 years 87 females median LLFDI 72 31 range 44 33 100 performing the 30CST and TUG while a smartphone was attached to their lower back The number of 30CST repetitions and the stopwatch based TUG duration were recorded Instrumented features were computed from the smartphone embedded inertial sensors Four logistic regression models were fitted and the Areas Under the Receiver Operating Curve AUC were calculated and compared using the DeLong test Standard clinical and instrumented measures of 30CST both showed equal moderate discriminative ability of 0 68 95 CI 0 60 0 76 p 0 97 Similarly for TUG AUC was 0 68 95 CI 0 60 0 77 and 0 65 95 CI 0 56 0 73 respectively p 0 26 In conclusion both clinical and instrumented measures recorded through a smartphone can discriminate early functional decline in healthy adults aged 61 70 years
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    Rebooting resilience: shifts toward dynamic, multi-level, and technology-based approaches for people living with HIV.
    (0000-00-00) Harrison, Sayward; Li, Xiaoming
    Resilience research has often been characterized by a static conceptualization of resilience that focuses on individual level factors that help people living with HIV PLHIV adapt to HIV related challenges and overcome other life adversities Early conceptualizations often depicted resilience as a static stable construct with limited attention paid to the social context and broader systems that may foster or discourage resilient adaptation across time and place This special issue seeks to challenge these conventional views by highlighting innovative HIV resilience research across the globe Far from ignoring socio cultural contexts studies presented in this issue directly address systemic stigma and discrimination against PLHIV as well as sexual and gender minority individuals and identify unique opportunities to promote resilience through building strong villages i e social networks reducing structural inequities and enhancing HIV treatment and care systems In addition papers included in this issue address the promise and challenges of utilizing mobile Heath mHealth technology to build resilience for PLHIV through improving psychosocial and clinical outcomes