Browsing by Author "Wasieloski, Leonard"
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- ItemOligonucleotide fingerprint identification for microarray-based pathogen diagnostic assays.(2006-12-20) Tembe, Waibhav; Zavaljevski, Nela; Bode, Elizabeth; Chase, Catherine; Geyer, Jeanne; Wasieloski, Leonard; Benson, Gary; Reifman, JaquesAdvances in DNA microarray technology and computational methods have unlocked new opportunities to identify DNA fingerprints i e oligonucleotide sequences that uniquely identify a specific genome We present an integrated approach for the computational identification of DNA fingerprints for design of microarray based pathogen diagnostic assays We provide a quantifiable definition of a DNA fingerprint stated both from a computational as well as an experimental point of view and the analytical proof that all in silico fingerprints satisfying the stated definition are found using our approach