Browsing by Author "Larsen, Mark E"
Now showing 1 - 4 of 4
Results Per Page
Sort Options
- ItemChemotherapy side-effect management using mobile phones.(2009-02-16) Larsen, Mark E; Rowntree, Joanna; Young, Annie M; Pearson, Sarah; Smith, Justine; Gibson, Oliver J; Weaver, Andrew; Tarassenko, LionelColorectal cancer is a major health problem in developed countries accounting for a significant proportion of deaths in the population Advances in chemotherapy treatment have led to therapy being delivered in the home setting which presents challenges in ensuring that treatment related side effects are detected and reported to clinical staff in an appropriate time frame A telemedicine system has been developed using a mobile phone platform to allow patients to complete symptom diaries which trigger alerts paged to their nurse in the event of severe side effects Six patients used this system for two cycles of oral chemotherapy Two cases of moderate symptoms deteriorating to more severe conditions were observed and individual self care and treatment advice were presented to these patients
- ItemMobile health for drug dose optimisation.(2012-01-18) Larsen, Mark E; Farmer, Andrew; Weaver, Andrew; Young, Annie; Tarassenko, LionelMobile health monitoring in the management of long term conditions has potential benefits for patient care especially when coupled with active adjustment of medication dosage We report studies of patient led self titration of oral glucose lowering medication OGLM and insulin in type 2 diabetes and dose adjustments including dose increases in oral chemotherapy for metastatic colorectal or breast cancer Monitoring compliance was high in each case and the feasibility of patients self titrating OGLM or insulin following an agreed treatment plan was demonstrated Chemotherapy dose increases supported by detailed toxicity profiles collected by phone have also been demonstrated
- ItemSmartphones, Sensors, and Machine Learning to Advance Real-Time Prediction and Interventions for Suicide Prevention: a Review of Current Progress and Next Steps.(0000-00-00) Torous, John; Larsen, Mark E; Depp, Colin; Cosco, Theodore D; Barnett, Ian; Nock, Matthew K; Firth, JoePURPOSE OF REVIEW As rates of suicide continue to rise there is urgent need for innovative approaches to better understand predict and care for those at high risk of suicide Numerous mobile and sensor technology solutions have already been proposed are in development or are already available today This review seeks to assess their clinical evidence and help the reader understand the current state of the field RECENT FINDINGS Advances in smartphone sensing machine learning methods and mobile apps directed towards reducing suicide offer promising evidence however most of these innovative approaches are still nascent Further replication and validation of preliminary results is needed Whereas numerous promising mobile and sensor technology based solutions for real time understanding predicting and caring for those at highest risk of suicide are being studied today their clinical utility remains largely unproven However given both the rapid pace and vast scale of current research efforts we expect clinicians will soon see useful and impactful digital tools for this space within the next 2 to 5 years
- ItemTelemedicine-supported insulin optimisation in primary care.(2010-11-25) Larsen, Mark E; Turner, Jane; Farmer, Andrew; Neil, Andrew; Tarassenko, LionelWe investigated the feasibility of a mobile phone based system for patients with type 2 diabetes who had recently commenced insulin therapy but remained poorly controlled The system was evaluated in a feasibility study in a general practice setting with 23 patients over six months A total of 22 patients successfully completed the study and used the system for a mean of 217 days range 162 376 Blood glucose control improved as reflected by a mean decrease in HbA 1c of 0 66 P 0 05 with the mean insulin dose increasing by 17 units P 0 006 Blood glucose monitoring compliance was high with readings available for 6 2 days per week although use of the mobile phone decreased during the study On average the mobile phone diary was used for 3 5 days per week Insulin dose adjustments were made throughout the study by all patients but not as frequently as would be expected for the degree of hyperglycaemia observed