Browsing by Author "Jack, Clifford R"
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- ItemDelphi definition of the EADC-ADNI Harmonized Protocol for hippocampal segmentation on magnetic resonance.(2014-08-18) Boccardi, Marina; Bocchetta, Martina; Apostolova, Liana G; Barnes, Josephine; Bartzokis, George; Corbetta, Gabriele; DeCarli, Charles; deToledo-Morrell, Leyla; Firbank, Michael; Ganzola, Rossana; Gerritsen, Lotte; Henneman, Wouter; Killiany, Ronald J; Malykhin, Nikolai; Pasqualetti, Patrizio; Pruessner, Jens C; Redolfi, Alberto; Robitaille, Nicolas; Soininen, Hilkka; Tolomeo, Daniele; Wang, Lei; Watson, Craig; Wolf, Henrike; Duvernoy, Henri; Duchesne, Simon; Jack, Clifford R; Frisoni, Giovanni B; ,This study aimed to have international experts converge on a harmonized definition of whole hippocampus boundaries and segmentation procedures to define standard operating procedures for magnetic resonance MR based manual hippocampal segmentation
- ItemThe EADC-ADNI Harmonized Protocol for manual hippocampal segmentation on magnetic resonance: Evidence of validity.(2014-09-30) Frisoni, Giovanni B; Jack, Clifford R; Bocchetta, Martina; Bauer, Corinna; Frederiksen, Kristian S; Liu, Yawu; Preboske, Gregory; Swihart, Tim; Blair, Melanie; Cavedo, Enrica; Grothe, Michel J; Lanfredi, Mariangela; Martinez, Oliver; Nishikawa, Masami; Portegies, Marileen; Stoub, Travis; Ward, Chadwich; Apostolova, Liana G; Ganzola, Rossana; Wolf, Dominik; Barkhof, Frederik; Bartzokis, George; DeCarli, Charles; Csernansky, John G; deToledo-Morrell, Leyla; Geerlings, Mirjam I; Kaye, Jeffrey; Killiany, Ronald J; Lehéricy, Stephane; Matsuda, Hiroshi; O'Brien, John; Silbert, Lisa C; Scheltens, Philip; Soininen, Hilkka; Teipel, Stefan; Waldemar, Gunhild; Fellgiebel, Andreas; Barnes, Josephine; Firbank, Michael; Gerritsen, Lotte; Henneman, Wouter; Malykhin, Nikolai; Pruessner, Jens C; Wang, Lei; Watson, Craig; Wolf, Henrike; deLeon, Mony; Pantel, Johannes; Ferrari, Clarissa; Bosco, Paolo; Pasqualetti, Patrizio; Duchesne, Simon; Duvernoy, Henri; Boccardi, Marina; ,An international Delphi panel has defined a harmonized protocol HarP for the manual segmentation of the hippocampus on MR The aim of this study is to study the concurrent validity of the HarP toward local protocols and its major sources of variance
- ItemEstablishing magnetic resonance images orientation for the EADC-ADNI manual hippocampal segmentation protocol.(2014-09-08) Boccardi, Marina; Bocchetta, Martina; Apostolova, Liana G; Preboske, Gregory; Robitaille, Nicolas; Pasqualetti, Patrizio; Collins, Louis D; Duchesne, Simon; Jack, Clifford R; Frisoni, Giovanni B; ,An effort to define and validate a Harmonized Protocol for standard hippocampal segmentation is being carried out We wished to estimate the effect of magnetic resonance image MRI spatial orientation on manual hippocampal segmentations to define optimal standard orientation of MRIs for hippocampal volumetry
- ItemHarmonization of magnetic resonance-based manual hippocampal segmentation: a mandatory step for wide clinical use.(2011-03-18) Frisoni, Giovanni B; Jack, Clifford RHippocampal atrophy is a marker of disease state and progression in Alzheimer s disease The gold standard to measure hippocampal volume is through manual segmentation A number of protocols to measure hippocampal volume through manual segmentation have been developed but the marked heterogeneity of anatomical landmarks has given rise to wide variability of volume estimates With the aim of fostering the use of hippocampal volume in routine clinical settings an international task force is currently working on developing a harmonized protocol that will resolve and reduce the present heterogeneity The task force will then validate the harmonized protocol develop harmonized probabilistic hippocampal maps and develop illustrative and educational material on the use of the harmonized protocol and maps
- ItemHarmonized benchmark labels of the hippocampus on magnetic resonance: The EADC-ADNI project.(2014-09-16) Bocchetta, Martina; Boccardi, Marina; Ganzola, Rossana; Apostolova, Liana G; Preboske, Gregory; Wolf, Dominik; Ferrari, Clarissa; Pasqualetti, Patrizio; Robitaille, Nicolas; Duchesne, Simon; Jack, Clifford R; Frisoni, Giovanni B; ,A globally harmonized protocol HarP for manual hippocampal segmentation based on magnetic resonance has been recently developed by a task force from European Alzheimer s Disease Consortium EADC and Alzheimer s Disease Neuroimaging Initiative ADNI Our aim was to produce benchmark labels based on the HarP for manual segmentation
- ItemManual segmentation qualification platform for the EADC-ADNI harmonized protocol for hippocampal segmentation project.(2015-01-24) Duchesne, Simon; Valdivia, Fernando; Robitaille, Nicolas; Mouiha, Abderazzak; Valdivia, F Abiel; Bocchetta, Martina; Apostolova, Liana G; Ganzola, Rossana; Preboske, Greg; Wolf, Dominik; Boccardi, Marina; Jack, Clifford R; Frisoni, Giovanni B; ,The use of hippocampal volumetry as a biomarker for Alzheimer s disease AD requires that tracers from different laboratories comply with the same segmentation method Here we present a platform for training and qualifying new tracers to perform the manual segmentation of the hippocampus on magnetic resonance images MRI following the European Alzheimer s Disease Consortium and Alzheimer s Disease Neuroimaging Initiative EADC ADNI Harmonized Protocol HarP Our objective was to demonstrate that the training process embedded in the platform leads to increased compliance and qualification with the HarP
- ItemRelationship between hippocampal atrophy and neuropathology markers: A 7T MRI validation study of the EADC-ADNI Harmonized Hippocampal Segmentation Protocol.(2015-01-26) Apostolova, Liana G; Zarow, Chris; Biado, Kristina; Hurtz, Sona; Boccardi, Marina; Somme, Johanne; Honarpisheh, Hedieh; Blanken, Anna E; Brook, Jenny; Tung, Spencer; Lo, Darrick; Ng, Denise; Alger, Jeffry R; Vinters, Harry V; Bocchetta, Martina; Duvernoy, Henri; Jack, Clifford R; Frisoni, Giovanni; ,The pathologic validation of European Alzheimer s Disease Consortium Alzheimer s Disease Neuroimaging Center Harmonized Hippocampal Segmentation Protocol HarP
- ItemTraining labels for hippocampal segmentation based on the EADC-ADNI harmonized hippocampal protocol.(2015-01-24) Boccardi, Marina; Bocchetta, Martina; Morency, Félix C; Collins, D Louis; Nishikawa, Masami; Ganzola, Rossana; Grothe, Michel J; Wolf, Dominik; Redolfi, Alberto; Pievani, Michela; Antelmi, Luigi; Fellgiebel, Andreas; Matsuda, Hiroshi; Teipel, Stefan; Duchesne, Simon; Jack, Clifford R; Frisoni, Giovanni B; ,The European Alzheimer s Disease Consortium and Alzheimer s Disease Neuroimaging Initiative ADNI Harmonized Protocol HarP is a Delphi definition of manual hippocampal segmentation from magnetic resonance imaging MRI that can be used as the standard of truth to train new tracers and to validate automated segmentation algorithms Training requires large and representative data sets of segmented hippocampi This work aims to produce a set of HarP labels for the proper training and certification of tracers and algorithms