Browsing by Author "Hansson Mild, Kjell"
Now showing 1 - 15 of 15
Results Per Page
Sort Options
- ItemCase-control study on cellular and cordless telephones and the risk for acoustic neuroma or meningioma in patients diagnosed 2000-2003.(2005-08-24) Hardell, Lennart; Carlberg, Michael; Hansson Mild, KjellWe performed a case control study on the use of cellular and cordless telephones and the risk for brain tumors We report the results for benign brain tumors with data from 413 cases 89 response rate 305 with meningioma 84 with acoustic neuroma 24 with other types and 692 controls 84 response rate For meningioma analogue phones yielded odds ratio OR 1 7 95 confidence interval CI 0 97 3 0 increasing to OR 2 1 95 CI 1 1 4 3 with a 10 year latency period Also digital cellular phones and cordless phones increased the risk to some extent For acoustic neuroma analogue phones gave OR 4 2 95 CI 1 8 10 increasing to OR 8 4 95 CI 1 6 45 with a 15 year latency period but based on low numbers Digital phones yielded OR 2 0 95 CI 1 05 3 8 whereas for cordless phones OR was not significantly increased In the multivariate analysis analogue phones represented a significant risk factor for acoustic neuroma
- ItemChildhood brain tumour risk and its association with wireless phones: a commentary.(2012-02-14) Söderqvist, Fredrik; Carlberg, Michael; Hansson Mild, Kjell; Hardell, LennartCase control studies on adults point to an increased risk of brain tumours glioma and acoustic neuroma associated with the long term use of mobile phones Recently the first study on mobile phone use and the risk of brain tumours in children and adolescents CEFALO was published It has been claimed that this relatively small study yielded reassuring results of no increased risk We do not agree We consider that the data contain several indications of increased risk despite low exposure short latency period and limitations in the study design analyses and interpretation The information certainly cannot be used as reassuring evidence against an association for reasons that we discuss in this commentary
- ItemEpidemiological evidence for an association between use of wireless phones and tumor diseases.(2009-07-27) Hardell, Lennart; Carlberg, Michael; Hansson Mild, KjellDuring recent years there has been increasing public concern on potential cancer risks from microwave emissions from wireless phones We evaluated the scientific evidence for long term mobile phone use and the association with certain tumors in case control studies mostly from the Hardell group in Sweden and the Interphone study group Regarding brain tumors the meta analysis yielded for glioma odds ratio OR 1 0 95 confidence interval CI 0 9 1 1 OR increased to 1 3 95 CI 1 1 1 6 with 10 year latency period with highest risk for ipsilateral exposure same side as the tumor localisation OR 1 9 95 CI 1 4 2 4 lower for contralateral exposure opposite side OR 1 2 95 CI 0 9 1 7 Regarding acoustic neuroma OR 1 0 95 CI 0 8 1 1 was calculated increasing to OR 1 3 95 CI 0 97 1 9 with 10 year latency period For ipsilateral exposure OR 1 6 95 CI 1 1 2 4 and for contralateral exposure OR 1 2 95 CI 0 8 1 9 were found Regarding meningioma no consistent pattern of an increased risk was found Concerning age highest risk was found in the age group Under20 years at time of first use of wireless phones in the studies from the Hardell group For salivary gland tumors non Hodgkin lymphoma and testicular cancer no consistent pattern of an association with use of wireless phones was found One study on uveal melanoma yielded for probable certain mobile phone use OR 4 2 95 CI 1 2 14 5 One study on intratemporal facial nerve tumor was not possible to evaluate due to methodological shortcomings In summary our review yielded a consistent pattern of an increased risk for glioma and acoustic neuroma after 10 year mobile phone use We conclude that current standard for exposure to microwaves during mobile phone use is not safe for long term exposure and needs to be revised
- ItemExposure to an 890-MHz mobile phone-like signal and serum levels of S100B and transthyretin in volunteers.(2009-06-22) Söderqvist, Fredrik; Carlberg, Michael; Hansson Mild, Kjell; Hardell, LennartWhether low intensity non thermal microwave radiation alters the integrity of the blood brain barrier has been debated since the late 1970s yet no experimental study has been carried out on humans The aim of this study was to test using peripheral markers whether exposure to a mobile phone like signal alters the integrity of the human blood brain and blood cerebrospinal fluid barriers A provocation study was carried out that exposed 41 volunteers to a 30 min GSM 890 MHz signal with an average specific energy absorption rate distribution of 1 0 W kg in the temporal area of the head as measured over any 1g of contiguous tissue The outcome was assessed by changes in serum concentrations of two putative markers of brain barrier integrity S100B and transthyretin Repeated blood sampling before and after the provocation showed no statistically significant increase in the serum levels of S100B while for transthyretin a statistically significant increase was seen in the final blood sample 60 min after the end of the provocation as compared to the prior sample taken immediately after provocation p 0 02 The clinical significance of this finding if any is unknown Further randomized studies with use of additional more brain specific markers are needed
- ItemMeningioma patients diagnosed 2007-2009 and the association with use of mobile and cordless phones: a case-control study.(2014-07-23) Carlberg, Michael; Söderqvist, Fredrik; Hansson Mild, Kjell; Hardell, LennartTo study the association between use of wireless phones and meningioma
- ItemMeta-analysis of long-term mobile phone use and the association with brain tumours.(2008-04-21) Hardell, Lennart; Carlberg, Michael; Söderqvist, Fredrik; Hansson Mild, KjellWe evaluated long term use of mobile phones and the risk for brain tumours in case control studies published so far on this issue We identified ten studies on glioma and meta analysis yielded OR 0 9 95 CI 0 8 1 1 Latency period of or 10 years gave OR 1 2 95 CI 0 8 1 9 based on six studies for ipsilateral use same side as tumour OR 2 0 95 CI 1 2 3 4 four studies but contralateral use did not increase the risk significantly OR 1 1 95 CI 0 6 2 0 Meta analysis of nine studies on acoustic neuroma gave OR 0 9 95 CI 0 7 1 1 increasing to OR 1 3 95 CI 0 6 2 8 using or 10 years latency period four studies Ipsilateral use gave OR 2 4 95 CI 1 1 5 3 and contra lateral OR 1 2 95 CI 0 7 2 2 in the or 10 years latency period group three studies Seven studies gave results for meningioma yielding overall OR 0 8 95 CI 0 7 0 99 Using or 10 years latency period OR 1 3 95 CI 0 9 1 8 was calculated four studies increasing to OR 1 7 95 CI 0 99 3 1 for ipsilateral use and OR 1 0 95 CI 0 3 3 1 for contralateral use two studies We conclude that this meta analysis gave a consistent pattern of an association between mobile phone use and ipsilateral glioma and acoustic neuroma using or 10 years latency period
- ItemMobile phone use and the risk for malignant brain tumors: a case-control study on deceased cases and controls.(2010-08-17) Hardell, Lennart; Carlberg, Michael; Hansson Mild, KjellWe investigated the use of mobile or cordless phones and the risk for malignant brain tumors in a group of deceased cases Most previous studies have either left out deceased cases of brain tumors or matched them to living controls and therefore a study matching deceased cases to deceased controls is warranted Recall error is one issue since it has been claimed that increased risks reported in some studies could be due to cases blaming mobile phones as a cause of the disease This should be of less importance for deceased cases and if cancer controls are used In this study brain tumor cases aged 20 80 years diagnosed during 1997 2003 that had died before inclusion in our previous studies on the same topic were included Two control groups were used one with controls that had died from another type of cancer than brain tumor and one with controls that had died from other diseases Exposure was assessed by a questionnaire sent to the next of kin for both cases and controls Replies were obtained for 346 75 cases 343 74 cancer controls and 276 60 controls with other diseases Use of mobile phones gave an increased risk highest in the 10 years latency group yielding odds ratio OR 2 4 and 95 confidence interval CI 1 4 4 1 The risk increased with cumulative number of lifetime hours for use and was highest in the 2 000 h group OR 3 4 95 CI 1 6 7 1 No clear association was found for use of cordless phones although OR 1 7 95 CI 0 8 3 4 was found in the group with 2 000 h of cumulative use This investigation confirmed our previous results of an association between mobile phone use and malignant brain tumors
- ItemMobile telephones and cancer: is there really no evidence of an association? (review).(2003-06-06) Hansson Mild, Kjell; Hardell, Lennart; Kundi, Michael; Mattsson, Mats-OlofTwo Swedish epidemiological studies have shown an association between the use of mobile telephones mainly of the analogue type and brain tumours These findings have been corroborated in a Finnish study Supportive evidence has also come from studies in USA but these investigations as well as a Danish study are inconclusive due to e g few exposed subjects short latency periods and methodological shortcomings The Swedish Radiation Protection Authority SSI engaged two epidemiologists from a private company to conduct a review of the literature They claimed that use of mobile telephones is not associated with increased risk for brain tumours Their conclusion was however based on an unbalanced view of current literature in favour of studies showing no association These circumstances are further explored in this communication
- ItemOwnership and use of wireless telephones: a population-based study of Swedish children aged 7-14 years.(2007-07-03) Söderqvist, Fredrik; Hardell, Lennart; Carlberg, Michael; Hansson Mild, KjellRecent years have seen a rapid increase in the use of mobile phones and other sources of microwave radiation raising concerns about possible adverse health effects As children have longer expected lifetime exposures to microwaves from these devices than adults who started to use them later in life they are a group of special interest
- ItemPooled analysis of case-control studies on malignant brain tumours and the use of mobile and cordless phones including living and deceased subjects.(2011-03-22) Hardell, Lennart; Carlberg, Michael; Hansson Mild, KjellWe studied the association between use of mobile and cordless phones and malignant brain tumours Pooled analysis was performed of two case control studies on patients with malignant brain tumours diagnosed during 1997 2003 and matched controls alive at the time of study inclusion and one case control study on deceased patients and controls diagnosed during the same time period Cases and controls or relatives to deceased subjects were interviewed using a structured questionnaire Replies were obtained for 1 251 85 cases and 2 438 84 controls The risk increased with latency period and cumulative use in hours for both mobile and cordless phones Highest risk was found for the most common type of glioma astrocytoma yielding in the 10 year latency group for mobile phone use odds ratio OR 2 7 95 confidence interval CI 1 9 3 7 and cordless phone use OR 1 8 95 CI 1 2 2 9 In a separate analysis these phone types were independent risk factors for glioma The risk for astrocytoma was highest in the group with first use of a wireless phone before the age of 20 mobile phone use OR 4 9 95 CI 2 2 11 cordless phone use OR 3 9 95 CI 1 7 8 7 In conclusion an increased risk was found for glioma and use of mobile or cordless phone The risk increased with latency time and cumulative use in hours and was highest in subjects with first use before the age of 20
- ItemPooled analysis of two case-control studies on the use of cellular and cordless telephones and the risk of benign brain tumours diagnosed during 1997-2003.(2006-01-04) Hardell, Lennart; Carlberg, Michael; Hansson Mild, KjellThe use of cellular and cordless telephones and the risk of brain tumours is of concern since the brain is a high exposure area We present the results of a pooled analysis of two case control studies on benign brain tumours diagnosed during 1997 2003 including answers from 1 254 88 cases and 2 162 89 controls aged 20 80 years For acoustic neuroma the use of analogue cellular phones gave an odds ratio OR of 2 9 and a 95 confidence interval CI of 2 0 4 3 for digital cellular phones OR 1 5 95 CI 1 1 2 1 and for cordless telephones OR 1 5 95 CI 1 04 2 0 The highest OR was found for analogue phones with a latency period of 15 years OR 3 8 95 CI 1 4 10 Regarding meningioma the results were as follows for analogue phones OR 1 3 95 CI 0 99 1 7 for digital phones OR 1 1 95 CI 0 9 1 3 and for cordless phones OR 1 1 95 CI 0 9 1 4 In the multivariate analysis a significantly increased risk of acoustic neuroma was found with the use of analogue phones
- ItemPooled analysis of two case-control studies on use of cellular and cordless telephones and the risk for malignant brain tumours diagnosed in 1997-2003.(2006-08-15) Hardell, Lennart; Carlberg, Michael; Hansson Mild, KjellTo study the use of cellular and cordless telephones and the risk for malignant brain tumours
- ItemRe-analysis of risk for glioma in relation to mobile telephone use: comparison with the results of the Interphone international case-control study.(2011-08-17) Hardell, Lennart; Carlberg, Michael; Hansson Mild, Kjell
- ItemSubjective symptoms among mobile phone users--a consequence of absorption of radiofrequency fields?(2003-04-01) Wilén, Jonna; Sandström, Monica; Hansson Mild, KjellIn a previous epidemiological study where we studied the prevalence of subjective symptoms among mobile phone MP users we found as an interesting side finding that the prevalence of many of the subjective symptoms increased with increasing calling time and number of calls per day In this extrapolative study we have selected 2402 people from the epidemiological study who used any of the four most common GSM MP We used the information about the prevalence of symptoms calling time per day and number of calls per day and combined it with measurements of the Specific Absorption Rate SAR We defined three volumes in the head and measured the maximum SAR averaged over a cube of 1 g tissue SAR 1g in each volume Two new exposure parameters Specific Absorption per Day SAD and Specific Absorption per Call SAC have been devised and are obtained as combinations of SAR calling time per day and number of calls per day respectively The results indicates that SAR values 0 5 W kg may be an important factor for the prevalence of some of the symptoms especially in combination with long calling times per day
- ItemVestibular schwannoma, tinnitus and cellular telephones.(2003-03-11) Hardell, Lennart; Hansson Mild, Kjell; Sandström, Monica; Carlberg, Michael; Hallquist, Arne; Påhlson, AnneliCases with tinnitus after using analogue cellular telephones are presented An increased odds ratio of 3 45 95 confidence interval CI 1 77 6 76 was found for vestibular schwannoma VS associated with the use of analogue cell phones During the time period 1960 1998 the age standardized incidence of VS in Sweden significantly increased yearly by 2 53 CI 1 71 3 35 A significant increase in the incidence of VS was only found for the latter of the two time periods 1960 1979 and 1980 1998 For all other brain tumors taken together the incidence significantly increased yearly by 0 80 CI 0 59 1 02 for the time period 1960 1998 although the increase was only significant for benign tumors other than VS during 1960 1979