Browsing by Author "DeShazer, David"
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- ItemDBSecSys: a database of Burkholderia mallei secretion systems.(2014-07-25) Memišević, Vesna; Kumar, Kamal; Cheng, Li; Zavaljevski, Nela; DeShazer, David; Wallqvist, Anders; Reifman, JaquesBacterial pathogenicity represents a major public health concern worldwide Secretion systems are a key component of bacterial pathogenicity as they provide the means for bacterial proteins to penetrate host cell membranes and insert themselves directly into the host cells cytosol Burkholderia mallei is a Gram negative bacterium that uses multiple secretion systems during its host infection life cycle To date the identities of secretion system proteins for B mallei are not well known and their pathogenic mechanisms of action and host factors are largely uncharacterized