Filipinos Fit and Trim - A feasible and efficacious DPP-based intervention trial.

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0000-00-00
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Introduction Filipino Americans are at higher risk for obesity and related Type 2 diabetes T2D compared to other Asian subgroups and non Hispanic whites Yet there are limited research studies to reduce health disparities and improve health outcomes for Filipinos Weight loss lifestyle intervention trials such as the Diabetes Prevention Program DPP can reduce obesity and T2D risks through physical activity and healthy eating Methods Thus we conducted a pilot FitAndTrim DPP based intervention study a randomized controlled trial 3 month intervention augmented with mobile technology 3 month maintenance follow up with a waitlist control The objective assessed the intervention feasibility and potential efficacy to reduce T2D risks in Filipino Americans with overweight obesity The overall study goal was a mean 5 weight reduction Results Sixty seven eligible Filipino men and women were enrolled and randomized to either an intervention or waitlist control group Participant retention was 91 In Phase 1 baseline to 3 months the intervention group had greater weight reduction compared to the waitlist control 4 3 vs 0 88 cross level interaction 0 85 1 4 0 35 In Phase 2 3 to 6 months after receiving the FitAndTrim intervention the waitlist group also had similar significant weight reduction 4 8 0 75 0 92 0 58 A majority of intervention group 57 also maintained their weight loss Overall 41 of study participants achieved a 5 weight loss Conclusion The FitAndTrim intervention demonstrated feasibility and potential efficacy for Filipino Americans Findings warrant a further larger longer trial to test the FitAndTrim feasibility and effectiveness in a real world Filipino community setting ClinicalTrialsgov registration number NCT02278939
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