Pooled analysis of case-control studies on malignant brain tumours and the use of mobile and cordless phones including living and deceased subjects.

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2011-03-22
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We studied the association between use of mobile and cordless phones and malignant brain tumours Pooled analysis was performed of two case control studies on patients with malignant brain tumours diagnosed during 1997 2003 and matched controls alive at the time of study inclusion and one case control study on deceased patients and controls diagnosed during the same time period Cases and controls or relatives to deceased subjects were interviewed using a structured questionnaire Replies were obtained for 1 251 85 cases and 2 438 84 controls The risk increased with latency period and cumulative use in hours for both mobile and cordless phones Highest risk was found for the most common type of glioma astrocytoma yielding in the 10 year latency group for mobile phone use odds ratio OR 2 7 95 confidence interval CI 1 9 3 7 and cordless phone use OR 1 8 95 CI 1 2 2 9 In a separate analysis these phone types were independent risk factors for glioma The risk for astrocytoma was highest in the group with first use of a wireless phone before the age of 20 mobile phone use OR 4 9 95 CI 2 2 11 cordless phone use OR 3 9 95 CI 1 7 8 7 In conclusion an increased risk was found for glioma and use of mobile or cordless phone The risk increased with latency time and cumulative use in hours and was highest in subjects with first use before the age of 20
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