Childhood brain tumours and use of mobile phones: comparison of a case-control study with incidence data.

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2012-07-27
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The first case control study on mobile phone use and brain tumour risk among children and adolescents CEFALO study has recently been published In a commentary published in Environmental Health S derqvist and colleagues argued that CEFALO suggests an increased brain tumour risk in relation to wireless phone use In this article we respond and show why consistency checks of case control study results with observed time trends of incidence rates are essential given the well described limitations of case control studies and the steep increase of mobile phone use among children and adolescents during the last decade There is no plausible explanation of how a notably increased risk from use of wireless phones would correspond to the relatively stable incidence time trends for brain tumours among children and adolescents observed in the Nordic countries Nevertheless an increased risk restricted to heavy mobile phone use to very early life exposure or to rare subtypes of brain tumours may be compatible with stable incidence trends at this time and thus further monitoring of childhood brain tumour incidence rate time trends is warranted
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