Oligonucleotide fingerprint identification for microarray-based pathogen diagnostic assays.
No Thumbnail Available
Date
2006-12-20
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Advances in DNA microarray technology and computational methods have unlocked new opportunities to identify DNA fingerprints i e oligonucleotide sequences that uniquely identify a specific genome We present an integrated approach for the computational identification of DNA fingerprints for design of microarray based pathogen diagnostic assays We provide a quantifiable definition of a DNA fingerprint stated both from a computational as well as an experimental point of view and the analytical proof that all in silico fingerprints satisfying the stated definition are found using our approach