Mobile phone and cordless phone use and the risk for glioma - Analysis of pooled case-control studies in Sweden, 1997-2003 and 2007-2009.
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2014-12-03
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Abstract
We made a pooled analysis of two case control studies on malignant brain tumours with patients diagnosed during 1997 2003 and 2007 2009 They were aged 20 80 years and 18 75 years respectively at the time of diagnosis Only cases with histopathological verification of the tumour were included Population based controls matched on age and gender were used Exposures were assessed by questionnaire The whole reference group was used in the unconditional regression analysis adjusted for gender age year of diagnosis and socio economic index In total 1498 89 cases and 3530 87 controls participated Mobile phone use increased the risk of glioma OR 1 3 95 CI 1 1 1 6 overall increasing to OR 3 0 95 CI 1 7 5 2 in the 25 year latency group Use of cordless phones increased the risk to OR 1 4 95 CI 1 1 1 7 with highest risk in the 15 20 years latency group yielding OR 1 7 95 CI 1 1 2 5 The OR increased statistically significant both per 100h of cumulative use and per year of latency for mobile and cordless phone use Highest ORs overall were found for ipsilateral mobile or cordless phone use OR 1 8 95 CI 1 4 2 2 and OR 1 7 95 CI 1 3 2 1 respectively The highest risk was found for glioma in the temporal lobe First use of mobile or cordless phone before the age of 20 gave higher OR for glioma than in later age groups