Now showing items 1-10 of 19
Decision tool for the early diagnosis of trauma patient hypovolemia.
We present a classifier for use as a decision assist tool to identify a hypovolemic state in trauma patients during helicopter transport to a hospital when reliable acquisition of vital sign data may be difficult The ...
Evidence of probabilistic behaviour in protein interaction networks.
Data from high throughput experiments of protein protein interactions are commonly used to probe the nature of biological organization and extract functional relationships between sets of proteins What has not been appreciated ...
Oligonucleotide fingerprint identification for microarray-based pathogen diagnostic assays.
Advances in DNA microarray technology and computational methods have unlocked new opportunities to identify DNA fingerprints i e oligonucleotide sequences that uniquely identify a specific genome We present an integrated ...
DOVIS: an implementation for high-throughput virtual screening using AutoDock.
Molecular docking based virtual screening is an important tool in drug discovery that is used to significantly reduce the number of possible chemical compounds to be investigated In addition to the selection of a sound ...
Moving towards individualized performance models.
Individualized short-term core temperature prediction in humans using biomathematical models.
This study compares and contrasts the ability of three different mathematical modeling techniques to predict individual specific body core temperature variations during physical activity The techniques include a first ...
Providing statistical measures of reliability for body core temperature predictions.
This paper describes the use of a data driven autoregressive integrated moving average model to predict body core temperature in humans during physical activity We also propose a bootstrap technique to provide a measure ...
A high-throughput pipeline for designing microarray-based pathogen diagnostic assays.
We present a methodology for high throughput design of oligonucleotide fingerprints for microarray based pathogen diagnostic assays The oligonucleotide fingerprints or DNA microarray probes are designed for identifying ...
The development of PIPA: an integrated and automated pipeline for genome-wide protein function annotation.
Automated protein function prediction methods are needed to keep pace with high throughput sequencing With the existence of many programs and databases for inferring different protein functions a pipeline that properly ...
Genome-wide enzyme annotation with precision control: catalytic families (CatFam) databases.
In this article we present a new method termed CatFam Catalytic Families to automatically infer the functions of catalytic proteins which account for 20 40 of all proteins in living organisms and play a critical role in a ...